Identification of Secreted Antigen 3 from Babesia gibsoni▿

机译：鉴定来自巴贝斯球菌的分泌抗原3

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

摘要
著录项
相似文献
相关主题

摘要

A cDNA expression library of Babesia gibsoni was screened with the serum collected from a dog experimentally infected with B. gibsoni. A novel antigen sharing homology with secreted antigen 1 of B. gibsoni was isolated. The genomic analysis indicated that the BgSA3 gene exists as multicopies in the genome of B. gibsoni. The putative peptide encoded by the BgSA3 gene showed some characteristics of secreted proteins. The serum raised in mice immunized with the recombinant BgSA3 expressed in Escherichia coli could recognize a native parasite protein with a molecular mass of 70 kDa. Moreover, a sandwich enzyme-linked immunosorbent assay with anti-BgSA3 antibodies could detect the circulating BgSA3 in the blood plasma of dogs experimentally infected with B. gibsoni. The identification of BgSA3 provided a useful target for the development of a diagnostic test for detecting specific antibodies and circulating antigens.

机译：用从实验性感染了吉布森牛的狗中收集的血清筛选了巴贝斯吉布森牛的cDNA表达文库。分离出一种新的抗原，其与长双歧杆菌的分泌抗原1具有同源性。基因组分析表明，BgSA3基因在长双歧杆菌基因组中以多份形式存在。 BgSA3基因编码的假定肽显示出分泌蛋白的某些特征。用在大肠杆菌中表达的重组BgSA3免疫的小鼠体内培养的血清可以识别分子量为70 kDa的天然寄生虫蛋白。此外，用抗BgSA3抗体进行的夹心酶联免疫吸附测定可以检测实验感染了吉布森牛的狗血浆中循环的BgSA3。 BgSA3的鉴定为开发检测特异性抗体和循环抗原的诊断测试提供了有用的目标。

著录项

作者
Jia, Honglin; Terkawi, M. Alaa; Aboge, Gabriel Oluga; Goo, Youn-Kyoung; Ma, Liqing; Zhou, Jinlin; Nishikawa, Yoshifumi; Igarashi, Ikuo; Fujisaki, Kozo; Xuan, Xuenan;
展开▼
作者单位

展开▼
年度 2009
总页数
原文格式 PDF
正文语种 en
中图分类

相似文献

外文文献
中文文献
专利

1. Identification of Secreted Antigen 3 from Babesia gibsoni [J] . Honglin Jia, M. Alaa Terkawi, Gabriel Oluga Aboge, Clinical and vaccine immunology: CVI . 2009,第6期

机译：鉴定了长柄巴贝斯球菌分泌的抗原3
2. Identification of a novel gene encoding a secreted antigen 1 of Babesia gibsoni and evaluation of its use in serodiagnosis. [J] . Jia H, Zhou J, Ikadai H, The American Journal of Tropical Medicine and Hygiene . 2006,第5期

机译：鉴定一种新的基因，该基因编码长柄巴贝斯球菌的分泌抗原1，并评估其在血清学诊断中的用途。
3. Identification of an immunodominant Babesia gibsoni 47-kDa antigen. [J] . Goo Y. K., Jia H., Aboge G. O., The Journal of protozoology research . 2009,第2期

机译：鉴定具有免疫优势的吉贝斯贝氏菌47-kDa抗原。
4. RAPID DIAGNOSIS OF BABESIA GIBSONI USING POINT-OF-CARE INSULATED ISOTHERMIC POLYMERASE CHAIN REACTION ASSAY [C] . Kirsten Cooke, Patrick Frenzer, Julie K. Levy, Conference of the American^College^of^Veterinary^Internal^Medicine . 2016

机译：使用护理点绝缘的等温聚合酶链反应测定快速诊断Babesia Gibsoni
5. Characterization of antigens from sporozoites and merozoites of Babesia bovis involved in attachment and invasion of erythrocytes. [D] . Mosqueda, Juan. 2002

机译：牛巴贝斯虫子孢子和裂殖子抗原的特性涉及红细胞的附着和侵袭。
6. Identification of Secreted Antigen 3 from Babesia gibsoni [O] . Honglin Jia, M. Alaa Terkawi, Gabriel Oluga Aboge, 2009

机译：鉴定了吉贝斯贝氏菌分泌的抗原3
7. Identification and Expression of a 50-Kilodalton Surface Antigen of Babesia gibsoni and Evaluation of Its Diagnostic Potential in an Enzyme-Linked Immunosorbent Assay [O] . Fukumoto, Shinya, Xuan, Xuenan, Nishikawa, Yoshifumi, 2001

机译：吉贝斯贝氏菌50公斤表面抗原的鉴定，表达及其在酶联免疫吸附测定中的诊断潜力
8. Complement-Fixing and Indirect Fluorescent Antibodies in Sera of Dogs Experimentally Infected with 'Babesia gibsoni'. [R] . Botros, B. A. M., Maronpot, R. R. 1974

机译：实验感染'Babesia gibsoni'的狗血清中的补体固定和间接荧光抗体。

Identification of Secreted Antigen 3 from Babesia gibsoni▿

摘要

著录项

相似文献

相关主题

期刊订阅